Scientists have identified a genetic mutation – found in an Indiana Amish family – that may extend life by up to ten years, and are now testing an experimental “longevity” drug that recreates the effect.
The genetic mutation, discovered by Northwestern University in the US in an extended family of Old Order Amish living in the vicinity of Berne, Indiana, appears to protect against multiple aspects of biological ageing in humans.
Indiana Amish kindred with the mutation live more than 10 per cent longer and have 10 per cent longer telomeres ,a protective cap at the end of our chromosomes that is a biological marker of ageing compared to Amish kindred members who do not have the mutation.
Amish with this mutation also have significantly less diabetes and lower fasting insulin levels.
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